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What is RNA Polymerase and TSS Selection Dynamics about?
This study investigates the role of RNA polymerase (RNAP) interactions with the core recognition element (CRE) in determining transcription start site (TSS) selection during transcription initiation. Using high-throughput sequencing methods, the authors demonstrate that sequence-specific RNAP-CRE interactions significantly influence TSS selection by modulating the position of the transcription bubble. The findings highlight the importance of these interactions in understanding gene expression control in Esc
- Author
- jimmyshen555
- Language
- EN