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Synthesis and Biological Activity of 6-Substituted 5-Acetyl-4,7-dimethoxybenzofuran Derivatives by Mariola Krawiecka; Bożena Kuran; Jerzy Kossakowski; Marta Kierzkowska; Grażyna Młynarczyk; Julia Kazmierczak-Barańska; Karolina Królewska; Marcin Cieślak is a Chemistry article available to read on EtoBox.

What is Synthesis and Biological Activity of 6-Substituted 5-Acetyl-4,7-dimethoxybenzofuran Derivatives about?

## Abstract In the search for new antimicrobial and anticancer agents, a series of (aryl/heteroaryl-piperazino-alkyl)-substituted derivatives of benzo[__b__]furans were prepared. All compounds were characterized by ^1^H NMR, ^13^C NMR, ESI-MS spectra and elemental analyses. Most of the investigated compounds had no antimicrobial activity (MIC > 512 mg/L) except for **2l**, **2m** and **2o**, which showed activity against __Candida albicans__. None of the tested compounds showed significant anticancer activity in K562 and HeLa cells.

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Author
Mariola Krawiecka; Bożena Kuran; Jerzy Kossakowski; Marta Kierzkowska; Grażyna Młynarczyk; Julia Kazmierczak-Barańska; Karolina Królewska; Marcin Cieślak
Publisher
Walter de Gruyter GmbH
Published
2013
Language
EN
Field
Chemistry (Physical Sciences)