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In vitro differentiation of human fetal thymus, cord blood, and peripheral blood CD4+ T cells into IL-10-producing T cells: Implications for transplantation tolerance by Thierry Sornasse; H. Yssel; P.V. Larenas; J.E. de Vries; R. de Waal Malefyt is a Immunology and Microbiology article available to read on EtoBox.

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Introduction: Two glycoprotein families are located at the opposite ends of mudne cytomegalovirus (MCMV) genome. The m02 glycoprotein family has 15 members, and at least two of them potentially interfere with antigen presentation in the MHC class I pathway. The glycoprotein of 34 kDa encoded by the mO4 gene was identified by coprecipitation with MHC class I molecules from the cell surface of IFN-gamma treated fibroblasts. MaterlaIr and Methods: Glycoprotein maturation was studied by immunoprecipitation after metabolic labelling. Cell surface expression was followed by immunofluorescence and cell surface biotinylation. Recombinant viruses were

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Author

Thierry Sornasse; H. Yssel; P.V. Larenas; J.E. de Vries; R. de Waal Malefyt

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0165-2478)

Published

1997

Language

EN

Field

Immunology and Microbiology (Life Sciences)