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This study investigates the role of engram cells in memory consolidation and retrograde amnesia, demonstrating that these cells retain memory despite disruptions in synaptic strength and dendritic spine density caused by protein synthesis inhibitors. The researchers found that direct optogenetic activation of engram cells can retrieve memories even in the presence of amnesia, suggesting that specific connectivity patterns in these cells are essential for memory storage and retrieval. The findings indicate t

Author

Emilio Espinosa

Language

EN