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Merlin and Follenzi - 2020 - Escape or Fight Inhibitors in Hemophilia A by rahul.968.792 is a document available to read on EtoBox.

What is Merlin and Follenzi - 2020 - Escape or Fight Inhibitors in Hemophilia A about?

The document discusses the challenges of treating hemophilia A (HA) with factor VIII (FVIII) replacement therapy, particularly the formation of inhibitors that affect treatment efficacy in about 30% of patients. It reviews various strategies to prevent or eradicate these inhibitors, including immunomodulatory drugs, oral or transplacental delivery methods, and gene therapy approaches, aiming to improve immune tolerance induction (ITI) protocols. The authors highlight the need for innovative solutions to enh

Author

rahul.968.792

Language

EN