About this Medicine article
NIV-NAVA versus NCPAP immediately after birth in premature infants: A randomized controlled trial by Juyoung Lee; Vilhelmiina Parikka; Arata Oda; Linda Wallström; Liisa Lehtonen; Hanna Soukka is a Medicine article available to read on EtoBox.
Objective: To evaluate whether noninvasive-neurally adjusted ventilatory assist (NIV-NAVA) decrease respiratory efforts compared to nasal continuous positive airway pressure (NCPAP) during the first hours of life. Methods: Twenty infants born between 28 +0 and 31 +6 weeks were randomized to NIV-NAVA or NCPAP. Positive end-expiratory pressure was constantly kept at 6 cmH 2 O for both groups and the NAVA level was 1.0 cmH 2 O/μV for NIV-NAVA group. The electrical activity of diaphragm (Edi) were recorded for the first two hours. Results: Peak and minimum Edi decreased similarly in both groups (P = 0.98 and P = 0.59, respectively). Leakages were higher in the NIV-NAVA group than in the NCPAP group (P < 0.001). The neural apnea defined as a flat Edi for ≥ 5 s were less frequent in NIV-NAVA group than in NCPAP group (P = 0.046). Conclusions: Immediately applied NIV-NAVA in premature infants did not reduce breathing effort, measured as peak Edi. However, NIV-NAVA decreased neural apneic episodes compared to NCPAP.
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- Author
- Juyoung Lee; Vilhelmiina Parikka; Arata Oda; Linda Wallström; Liisa Lehtonen; Hanna Soukka
- Publisher
- Elsevier BV
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)