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Can I read Assessment of the Impact of Hydrolysis on Bound Sulfonamide Residue Determination in Honey Using Stable Isotope Dilution Ultrahigh Performance Liquid Chromatography Tandem Mass Spectrometry on EtoBox?
Assessment of the Impact of Hydrolysis on Bound Sulfonamide Residue Determination in Honey Using Stable Isotope Dilution Ultrahigh Performance Liquid Chromatography Tandem Mass Spectrometry by Yan Zhang; Xiu Qin Li; Zhen Guo; Xia Zhou; Shuang Qing Li; Xiao Min Li; Hui Jiao; Qing He Zhang is a Agricultural and Biological Sciences article available to read on EtoBox.
What is Assessment of the Impact of Hydrolysis on Bound Sulfonamide Residue Determination in Honey Using Stable Isotope Dilution Ultrahigh Performance Liquid Chromatography Tandem Mass Spectrometry about?
In this study, an analytical method based on isotope dilution-liquid chromatography tandem mass spectrometry (ID-LC-MS/MS) was developed as a candidate reference method for the determination of sulfonamides (SAs) in honey. To guarantee the accuracy and authenticity, the impact of hydrolysis on bound SA residues was first investigated by enabling (i) identification of sugar-bound SAs, (ii) clarifying the binding reaction rule between the SAs and sugar, (iii) detection of free SAs and sugar-bound SAs, and (iv) preparation of SA-contaminated honey. Thus, the efficiency of different hydrolysis conditions was assessed by comparing the bound SA content before and after hydrolysis. In addition, optimization of the sample pretreatment procedures and LC conditions to minimize matrix effects by separation from significant matrix interferences was also performed. Satisfactory results in terms of hydrolysis efficiency (approximately 88.3%-99.2%), extraction efficiency (84.2%-105.3%), recovery (95.9%-103.1%), and limit of quantification (0.6-1.5 μg⋅kg -1 ) were obtained.
Who reads Assessment of the Impact of Hydrolysis on Bound Sulfonamide Residue Determination in Honey Using Stable Isotope Dilution Ultrahigh Performance Liquid Chromatography Tandem Mass Spectrometry?
It is typically read by researchers, students, and practitioners in Agricultural and Biological Sciences.
- Author
- Yan Zhang; Xiu Qin Li; Zhen Guo; Xia Zhou; Shuang Qing Li; Xiao Min Li; Hui Jiao; Qing He Zhang
- Publisher
- Elsevier BV
- Published
- 2021
- Language
- EN
- Field
- Agricultural and Biological Sciences (Life Sciences)