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Can I read Topotaxis of active Brownian particles on EtoBox?
Topotaxis of active Brownian particles by Koen Schakenraad; Linda Ravazzano; Niladri Sarkar; Joeri A. J. Wondergem; Roeland M. H. Merks; Luca Giomi is a Physics and Astronomy article available to read on EtoBox.
What is Topotaxis of active Brownian particles about?
Recent experimental studies have demonstrated that cellular motion can be directed by topographical gradients, such as those resulting from spatial variations in the features of a micropatterned substrate. This phenomenon, known as topotaxis, has been extensively studied for topographical gradients at the subcellular scale, but can also occur in the presence of a spatially varying density of cell-sized features. Such a large-scale topotaxis has recently been observed in highly motile cells that persistently crawl within an array of obstacles with smoothly varying lattice spacing. We introduce a toy model of large-scale topotaxis, based on active Brownian particles. Using numerical simulations and analytical arguments, we demonstrate that topographical gradients introduce a spatial modulation of the particles' persistence, leading to directed motion toward regions of higher persistence. Our results demonstrate that persistent motion alone is sufficient to drive large-scale topotaxis and could serve as a starting point for more detailed studies on self-propelled particles and cells.
Who reads Topotaxis of active Brownian particles?
It is typically read by researchers, students, and practitioners in Physics and Astronomy.
- Author
- Koen Schakenraad; Linda Ravazzano; Niladri Sarkar; Joeri A. J. Wondergem; Roeland M. H. Merks; Luca Giomi
- Publisher
- The American Physical Society; American Physical Society; American Physical Society (APS) (ISSN 1063-651X)
- Published
- 2020
- Language
- EN
- Field
- Physics and Astronomy (Physical Sciences)