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What is Revollo 2013 about?

The review discusses the regulation of Sirt1 activity, highlighting its crucial role in metabolism, stress responses, and aging through its dependence on NAD+ levels and various post-translational modifications (PTMs). Key mechanisms include phosphorylation, methylation, SUMOylation, and protein-protein interactions that fine-tune Sirt1

Author

Smendrick

Language

EN