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Analysis of chronic kidney disease staging with different estimated glomerular filtration rate equations in Chinese centenarians by Han, Qiu-Xia; Zhang, Dong; Zhao, Ya-Li; Liu, Liang; Li, Jing; Zhang, Fu; Luan, Fu-Xin; Duan, Jia-Yu; Liu, Zhang-Suo; Cai, Guang-Yan; Chen, Xiang-Mei; Zhu, Han-Yu is a Medicine article available to read on EtoBox.
What is Analysis of chronic kidney disease staging with different estimated glomerular filtration rate equations in Chinese centenarians about?
## Abstract ## Background: Accurate estimation of the glomerular filtration rate (GFR) and staging of chronic kidney disease (CKD) are important. Currently, there is no research on the differences in several estimated GFR equations for staging CKD in a large sample of centenarians. Thus, this study aimed to investigate the differences in CKD staging with the most commonly used equations and to analyze sources of discrepancy. ## Methods: A total of 966 centenarians were enrolled in this study from June 2014 to December 2016 in Hainan province, China. The GFR with the Modification of Diet in Renal Disease (MDRD), Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) and Berlin Initiative Study 1 (BIS1) equations were estimated. Agreement between these equations was investigated with the __κ__ statistic and Bland-Altman plots. Sources of discrepancy were investigated by partial correlation analysis. ## Results: The __κ__ values of the MDRD and CKD-EPI equations, MDRD and BIS1 equations, and CKD-EPI and BIS1 equations were 0.610, 0.253, and 0.381, respectively. Serum creatinine (Scr) explained 10.96%, 41.60% and 17.06% of the variability in these three comparisons, respectively.
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- Author
- Han, Qiu-Xia; Zhang, Dong; Zhao, Ya-Li; Liu, Liang; Li, Jing; Zhang, Fu; Luan, Fu-Xin; Duan, Jia-Yu; Liu, Zhang-Suo; Cai, Guang-Yan; Chen, Xiang-Mei; Zhu, Han-Yu
- Publisher
- Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins; Wolters Kluwer Medknow Publications; Ovid Technologies (Wolters Kluwer Health); Medknow; Beijing: Chinese Medical Association; Beijing: Chinese Medical Association; Mumbai: Wolters Kluwer Health (ISSN 0366-6999)
- Published
- 2019
- Language
- EN
- Field
- Medicine (Health Sciences)