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Reflux symptoms in general practice: diagnostic evaluation of the Carlsson–Dent gastro-oesophageal reflux disease questionnaire by M. E. Numans; N. J. De Wit is a Medicine article available to read on EtoBox.

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## Summary **Background** : Amongst primary care patients with dyspeptic symptoms, those with reflux‐like symptoms or gastro‐oesophageal reflux disease are expected to benefit most from empirical proton pump inhibitor therapy. Recognition of this patient group, however, is difficult. The Carlsson–Dent gastro‐oesophageal reflux disease questionnaire was developed to justify the selection of primary care patients for empirical proton pump inhibitor treatment. **Aim** : To evaluate the diagnostic test characteristics of the Carlsson–Dent questionnaire in a primary care population. **Methods** : A prospective, open‐label, multi‐centre diagnostic prevalence study was conducted amongst primary care adults with reflux symptoms. All patients completed the questionnaire and underwent gastroscopy. If no abnormalities were found, the patients were prescribed 2 weeks of treatment with omeprazole (20 mg daily). Receiver operating characteristic curve analysis was used to determine the overall discriminative value of the questionnaire. Diagnostic test characteristics of both the cut‐off score (total diagnostic score) in the questionnaire and the physician's provisional classification were measur

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Author

M. E. Numans; N. J. De Wit

Publisher

John Wiley and Sons; Blackwell Publishing; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley; Research Square (ISSN 0269-2813)

Published

2003

Language

EN

Field

Medicine (Health Sciences)