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Editor's Choice – Randomised Clinical Trial of Supervised Exercise Therapy vs. Endovascular Revascularisation for Intermittent Claudication Caused by Iliac Artery Obstruction: The SUPER study by Mark J.W. Koelemay; Nick S. van Reijen; Susan van Dieren; Franceline A. Frans; Erik J.G. Vermeulen; Hessel C.J.L. Buscher; Jim A. Reekers; M.G.W. Dijkgraaf; R.J. de Haan; R. Balm; M.M. Idu; J.D. Blankensteijn; A.W. Hoksbergen; A.P. Conijn; R. Met; D.A. Legemate; S. Bipat; K.P. van Lienden; O.M. van Delden; E.J. Zijlstra; K.P. van Lienden; R. Lely; R.H.H. Engelbert; M.A. van Egmond; A. Poelgeest; E. Geleijn; A.J. de Nie; M.A. Schreve; A. Kamphuis; R.H.J. Kropman; J. Wille; J.P.M.M. de Vries; R.H. van de Mortel; H.D. van de Pavoord; D.A. van den Heuvel; M. van Leersum; M.J. van Strijen; J.A. Vos; D. Nio; A. Rijbroek; G.J.M. Akkersdijk; R. Metz; B.J. van Kelckhoven; H.J. van de Rest; V.J. Leijdekkers; A.C. Vahl; R.C. van Nieuwenhuizen; J.G. Blomjous; A.D. Montauban van Swijndregt; P.P.C. Poyck; M. van der Jagt; J.A. van der Vliet; L.J. Schultze Kool; P.L. Klemm; H.W. Slis; M.C.M. Willems; L.C. Huisman; J.H.D. de Bruine; M.J. Mallant; L. Smeets; S.M. van Sterkenburg; M.M. Reijnen; P.B. Veendrick; M.H. van Werkum; J.A. van Ostayen; B.H.P. Elsman; L.G. van der Hem; R.B.M. van Tongeren; C.F.M. Klok; W.E. Hellings; J.C. Aarts; A.M. Wiersema; T.A. van den Broek; A. Moolhuijzen; J.A. Teijink; M.R. van Sambeek; B.P. Keller; G.A. Vos; J.C. Breek†; J. Gravendeel; R. Oosterhof-Berktas; N.A. Koedam; E.J. Hollander; T. Pels Rijcken; S.S. van der Voort; B. Honing; D.M. Scharn; M.S. Lemson; J. Seegers; R.M. Krol; C.J. Buskens; C.J. Zeebregts; R.A. de Bie; H. van Overhagen is a Medicine article available to read on EtoBox.

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## Objective: International guidelines recommend supervised exercise therapy (set) as primary treatment for all patients with intermittent claudication (ic), yet primary endovascular revascularisation (er) might be more effective in patients with iliac artery obstruction. ## Methods: This was a multicentre rct including patients with ic caused by iliac artery stenosis or occlusion (nct01385774). patients were allocated randomly to set or er stratified for maximum walking distance (mwd) and concomitant sfa disease. primary endpoints were mwd on a treadmill (3.2 km/h, 10% incline) and disease specific quality of life (vascuqol) after one year. additional interventions during a mean follow up of 5.5 years were recorded. ## Results: Between november 2010 and may 2015, 114 patients were allocated to set, and 126 to er. the trial was terminated prematurely after 240 patients were included. compliance with set was 57/114 (50%) after six months. ten patients allocated to er (8%) did not receive this intervention. one year follow up was complete for 90/114 (79%) set patients and for 104/126 (83%) er patients. the mean mwd improved from 187 to 561 m in set patients and from 196 to 574 m in e

Who reads Editor's Choice – Randomised Clinical Trial of Supervised Exercise Therapy vs. Endovascular Revascularisation for Intermittent Claudication Caused by Iliac Artery Obstruction: The SUPER study?

Author

Mark J.W. Koelemay; Nick S. van Reijen; Susan van Dieren; Franceline A. Frans; Erik J.G. Vermeulen; Hessel C.J.L. Buscher; Jim A. Reekers; M.G.W. Dijkgraaf; R.J. de Haan; R. Balm; M.M. Idu; J.D. Blankensteijn; A.W. Hoksbergen; A.P. Conijn; R. Met; D.A. Legemate; S. Bipat; K.P. van Lienden; O.M. van Delden; E.J. Zijlstra; K.P. van Lienden; R. Lely; R.H.H. Engelbert; M.A. van Egmond; A. Poelgeest; E. Geleijn; A.J. de Nie; M.A. Schreve; A. Kamphuis; R.H.J. Kropman; J. Wille; J.P.M.M. de Vries; R.H. van de Mortel; H.D. van de Pavoord; D.A. van den Heuvel; M. van Leersum; M.J. van Strijen; J.A. Vos; D. Nio; A. Rijbroek; G.J.M. Akkersdijk; R. Metz; B.J. van Kelckhoven; H.J. van de Rest; V.J. Leijdekkers; A.C. Vahl; R.C. van Nieuwenhuizen; J.G. Blomjous; A.D. Montauban van Swijndregt; P.P.C. Poyck; M. van der Jagt; J.A. van der Vliet; L.J. Schultze Kool; P.L. Klemm; H.W. Slis; M.C.M. Willems; L.C. Huisman; J.H.D. de Bruine; M.J. Mallant; L. Smeets; S.M. van Sterkenburg; M.M. Reijnen; P.B. Veendrick; M.H. van Werkum; J.A. van Ostayen; B.H.P. Elsman; L.G. van der Hem; R.B.M. van Tongeren; C.F.M. Klok; W.E. Hellings; J.C. Aarts; A.M. Wiersema; T.A. van den Broek; A. Moolhuijzen; J.A. Teijink; M.R. van Sambeek; B.P. Keller; G.A. Vos; J.C. Breek†; J. Gravendeel; R. Oosterhof-Berktas; N.A. Koedam; E.J. Hollander; T. Pels Rijcken; S.S. van der Voort; B. Honing; D.M. Scharn; M.S. Lemson; J. Seegers; R.M. Krol; C.J. Buskens; C.J. Zeebregts; R.A. de Bie; H. van Overhagen

Publisher

Elsevier BV

Published

2022

Language

EN

Field

Medicine (Health Sciences)