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Efficacy of Orthobiologic Adjuvants to Core Decompression for Hip Preservation in Avascular Necrosis Hip by Prasoon Kumar; Vijay D Shetty; Mandeep Singh Dhillon is a Medicine article available to read on EtoBox.

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## Abstract Head preserving modalities in avascular necrosis (AVN) hip are variably effective in early stages, and further options that could prevent head distortion and osteoarthritis are needed. Core decompression (CD) is the most commonly used surgery in the early stages of osteonecrosis with variable rates of success. The present review aimed to determine the effectiveness of bone marrow aspirate concentrate (BMAC), platelet-rich plasma (PRP), bone morphogenetic proteins (BMP) or their combination with CD in early stages of AVN hip, prior to collapse of femoral head. Additionally, any newer unexplored modalities were also searched for and ascertained. PubMed and SCOPUS databases were searched for relevant articles in English language describing CD with aforementioned orthobiologics. We analysed a total of 20 studies published between 2011 and 2020. There were 6 retrospective and 14 prospective studies. PRP showed improved survival and functional outcomes; however, with only three studies, there is inconclusive evidence for its routine utilization. BMAC enhances the efficacy of CD which can further be increased by culture and expansion of cells or combining it with PRP to stimul

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Author

Prasoon Kumar; Vijay D Shetty; Mandeep Singh Dhillon

Publisher

Oxford University Press

Published

2020

Language

EN

Field

Medicine (Health Sciences)