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Single‐dose antibiotic therapy for urinary infections during pregnancy: A systematic review and meta‐analysis of randomized clinical trials by Gabriel Schuch Schulz; Felipe Schütz; Felipe Valentim Jung Spielmann; Lucas Uglione da Ros; Júlia Stüker de Almeida; José Geraldo Lopes Ramos is a Medicine article available to read on EtoBox.
What is Single‐dose antibiotic therapy for urinary infections during pregnancy: A systematic review and meta‐analysis of randomized clinical trials about?
## Abstract ## Background During pregnancy, urinary infections are an important cause of maternofetal morbidity and mortality and may lead to several complications. ## Objective To verify whether the use of antibiotic therapy in a single dose when compared with multiple doses in lower tract urinary infections during pregnancy is effective to obtain microbiologic cure. ## Search strategy Online databases were searched. Keywords used were "single‐drug dose", "antibiotic", "fosfomycin", "amoxicillin", "trimethoprim", "pregnancy", and "urinary tract infection". ## Selection criteria Studies were included if they were randomized controlled trials, the population was pregnant woman, microbiologic cure was attained, and one of the treatment groups received single‐dose antibiotic therapy. ## Data collection and analysis Preselected studies have been independently read by pairs, and data were extracted according to a predetermined sheet. The Cochrane tool was used for the risk of bias. ## Main results A total of 1063 women from nine studies were included. The primary outcome was the microbiologic cure attested by urine culture. When compared with the multiple‐day use of antibiotics, the sin
Who reads Single‐dose antibiotic therapy for urinary infections during pregnancy: A systematic review and meta‐analysis of randomized clinical trials?
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- Author
- Gabriel Schuch Schulz; Felipe Schütz; Felipe Valentim Jung Spielmann; Lucas Uglione da Ros; Júlia Stüker de Almeida; José Geraldo Lopes Ramos
- Publisher
- Wiley
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)