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Echocardiographic Epicardial Adipose Tissue Thickness for Risk Stratification of Patients With Heart Failure by Parisi, Valentina; Conte, Maddalena; Petraglia, Laura; Grieco, Fabrizio Vincenzo; Bruzzese, Dario; Caruso, Aurelio; Grimaldi, Maria Gabriella; Campana, Pasquale; Gargiulo, Paola; Paolillo, Stefania; Attena, Emilio; Russo, Vincenzo; Galasso, Gennaro; Rapacciuolo, Antonio; Perrone Filardi, Pasquale; Leosco, Dario is a Medicine article available to read on EtoBox.

What is Echocardiographic Epicardial Adipose Tissue Thickness for Risk Stratification of Patients With Heart Failure about?

## Background and Aims Epicardial adipose tissue (EAT) has been shown to be involved in the pathogenesis and progression of heart failure (HF). In this study we aimed to explore the predictive value of echocardiographic EAT thickness on prognosis of a selected population of HF patients. ## Methods The patient population included n. 69 consecutive patients with systolic HF referred to implantable cardioverter defibrillator (ICD) implantation for primary or secondary prevention. At the time of enrolment, echocardiographic EAT thickness was assessed in all patients along with demographic and clinical data. The study had a median follow-up time of 49.8 months. We assessed the prognostic predictive value of EAT thickness on a composite clinical and arrhythmic outcome including HF related deaths, new hospital admissions for HF worsening, and atrial and life threatening ventricular arrhythmic events. Clinical and arrhythmic outcomes were also evaluated separately. ## Results At univariate analysis, EAT thickness significantly predicted all the three outcomes considered. Of interest, at multivariate analysis, after adjusting for known risk factor, EAT remained significantly associated to t

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Author

Parisi, Valentina; Conte, Maddalena; Petraglia, Laura; Grieco, Fabrizio Vincenzo; Bruzzese, Dario; Caruso, Aurelio; Grimaldi, Maria Gabriella; Campana, Pasquale; Gargiulo, Paola; Paolillo, Stefania; Attena, Emilio; Russo, Vincenzo; Galasso, Gennaro; Rapacciuolo, Antonio; Perrone Filardi, Pasquale; Leosco, Dario

Publisher

Frontiers; Frontiers Media SA; Frontiers Media S.A.; Lausanne: Frontiers Media S.A., 2010- (ISSN 1664-042X)

Published

2020

Language

EN

Field

Medicine (Health Sciences)