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Disappearance of a pituitary tumor after 15 months of treatment with CV 205–502, a new dopamine agonist by W. J. Faβbender; H. Stracke; G. Bachmann; W. Rau; K. Federlin is a Medicine article available to read on EtoBox.

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We report the case of a 27-year-old woman with a prolactin-secreting macroadenoma of the pituitary gland who was under treatment with a new dopamine agonist, Sandoz CV 205-502. Immediately after diagnosis of a 12 x 10 mm intrasellar prolactinoma, treatment with CV 205-502 was begun at a daily dose of 0.075 mg. Under this low dose, prolactin in the serum normalized after 4 weeks, the initial hormone value being 189.9 ng/ml. After 6 months of therapy there was still a 6 x 6 mm tumor, and after 15 months of treatment the pathological process could no longer be observed with magnetic resonance imaging. In the 20th month of therapy the patient became pregnant. An ovulatory menstrual cycle had been present for a few months.

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Author

W. J. Faβbender; H. Stracke; G. Bachmann; W. Rau; K. Federlin

Publisher

Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC (ISSN 1432-1440)

Published

1992

Language

EN

Field

Medicine (Health Sciences)