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The research article discusses enantioselective organocatalytic Michael additions of aldehydes to nitroalkenes using an ionically tagged diphenylprolinol silyl ether catalyst in ionic liquids. The method achieved high yields (up to 95%) and enantioselectivities (up to 95% ee), with some catalysts being reusable. This approach is significant for synthesizing biologically relevant compounds, including oseltamivir and its analogues.

Author

Ira Novita Sari

Language

EN