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PDGF BB and MCP 1 in HIV Neuroinflammation by door9harbor is a document available to read on EtoBox.

What is PDGF BB and MCP 1 in HIV Neuroinflammation about?

The document discusses the role of MCP 1 expression in astrocytes treated with PDGF BB and its implications for blood brain barrier disruption and neuroinflammation in HIV patients. It finds that PDGF BB induces MCP 1 expression through MAPK and PI3K Akt pathways and NFB activation. Conditioned media from PDGF BB treated astrocytes increased monocyte transmigration, an effect reduced by MCP 1 blocking antibodies. Increased MCP 1 expression may disrupt the blood brain barrier and recruit monocytes, exacerbat

Author

door9harbor

Language

EN