Opening book details…
Can I read Association of the apoptotic marker APO1/Fas with children’s predisposing factors for metabolic syndrome and with mean platelet volume on EtoBox?
Association of the apoptotic marker APO1/Fas with children’s predisposing factors for metabolic syndrome and with mean platelet volume by Maria Efthymia Katsa; Eirini Kostopoulou; Maria Magana; Anastasios Ioannidis; Stylianos Chatzipanagiotou; Athanasios Sachlas; Ioannis Dimopoulos; Bessie E. Spiliotis; Andrea Paola Rojas Gil is a Medicine article available to read on EtoBox.
What is Association of the apoptotic marker APO1/Fas with children’s predisposing factors for metabolic syndrome and with mean platelet volume about?
Background: Apoptosis antigen 1/FAS receptor (APO1/ Fas) signaling in endothelial cells plays a significant role in angiogenesis while increased mean platelet volume (MPV) is an important marker for platelet activation. We investigated the possible correlation between APO1/Fas and both metabolic parameters and platelet activity (indicated by the MPV) in a healthy pediatric population. Methods: One hundred and eighty-five children, aged 5-17 years old, were enrolled in the study. The participants were divided into subgroups according to their age and body mass index percentile (BMI%). APO1/Fas was measured by enzyme-linked immunosorbent assay (ELISA) and MPV by the MEK-6410K. Results: Eighty-one children (43.8%) had excess weight, which was more prevalent in children ≤9 years of age. Sixty-five children (35.1%) exhibited a predisposition for metabolic syndrome. A negative correlation was found between APO1/Fas and predisposing factors for metabolic syndrome: Glucose, cholesterol, uric acid, low-density lipoprotein (LDL), and triglycerides. In contrast, a positive correlation was found between APO1/Fas and C-reactive protein (CRP). Receiver operating characteristic (ROC) analysis sho
Who reads Association of the apoptotic marker APO1/Fas with children’s predisposing factors for metabolic syndrome and with mean platelet volume?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Maria Efthymia Katsa; Eirini Kostopoulou; Maria Magana; Anastasios Ioannidis; Stylianos Chatzipanagiotou; Athanasios Sachlas; Ioannis Dimopoulos; Bessie E. Spiliotis; Andrea Paola Rojas Gil
- Publisher
- Walter de Gruyter GmbH
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)