Can I read mRNA: A promising platform for cancer immunotherapy on EtoBox?

mRNA: A promising platform for cancer immunotherapy by Byoungjae Kong; Yelee Kim; Eun Hye Kim; Jung Soo Suk; Yoosoo Yang is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is mRNA: A promising platform for cancer immunotherapy about?

Messenger RNA (mRNA) is now in the limelight as a powerful tool for treating various human diseases, especially malignant tumors, thanks to the remarkable clinical outcomes of mRNA vaccines using lipid nanoparticle technology during the COVID-19 pandemic. Recent promising preclinical and clinical results that epitomize the advancement in mRNA and nanoformulation-based delivery technologies have highlighted the tremendous potential of mRNA in cancer immunotherapy. mRNAs can be harnessed for cancer immunotherapy in forms of various therapeutic modalities, including cancer vaccines, adoptive T-cell therapies, therapeutic antibodies, and immunomodulatory proteins. This review provides a comprehensive overview of the current state and prospects of mRNA-based therapeutics, including numerous delivery and therapeutic strategies.

Who reads mRNA: A promising platform for cancer immunotherapy?

Author

Byoungjae Kong; Yelee Kim; Eun Hye Kim; Jung Soo Suk; Yoosoo Yang

Publisher

Elsevier BV

Published

2023

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)