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Enhancing Itraconazole Solubility with Poloxamer 188 by yuppieraj is a document available to read on EtoBox.

What is Enhancing Itraconazole Solubility with Poloxamer 188 about?

The document describes a study that aimed to improve the solubility and dissolution rate of the poorly water-soluble drug itraconazole. Researchers prepared solid dispersions of itraconazole and the polymer poloxamer 188 using a hot melt method. They determined the eutectic point of the drug-polymer mixture using a cooling curve method and constructed a phase diagram. Solubility and dissolution tests found that poloxamer 188 significantly increased the solubility and dissolution rate of itraconazole compare

Author

yuppieraj

Language

EN