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French National Diagnostic and Care Protocol for antiphospholipid syndrome in adults and children by Z. Amoura; B. Bader-Meunier; C. BAL dit Sollier; A. Belot; Y. Benhamou; H. Bezanahary; F. Cohen; N. Costedoat-Chalumeau; L. Darnige; L. Drouet; E. Elefant; A. Harroche; M. Lambert; T. Martin; I. Martin-Toutain; A. Mathian; A. Mekinian; M. Pineton De Chambrun; L. de Pontual; D. Wahl; C. Yelnik; S. Zuily; D. Chauveau; J. Clouscard; C. Frere; E. Hachulla; I. Kone-Paut; D. Lasne; T. Lecompte; V. Le Guern; J. Ni Zard; T. Papo; M. Riviere; N. Schleinitz; B. Tossier is a Medicine article available to read on EtoBox.

What is French National Diagnostic and Care Protocol for antiphospholipid syndrome in adults and children about?

Antiphospholipid syndrome (APS) is a chronic autoimmune disease involving vascular thrombosis and/or obstetric morbidity and persistent antibodies to phospholipids or certain phospholipid-associated proteins. It is a rare condition in adults and even rarer in children. The diagnosis of APS can be facilitated by the use of classification criteria based on a combination of clinical and biological features. APS may be rapidly progressive with multiple, often synchronous thromboses, resulting in life-threatening multiple organ failure. This form is known as "catastrophic antiphospholipid syndrome" (CAPS). It may be primary or associated with systemic lupus erythematosus (associated APS) and in very rare cases with other systemic autoimmune diseases. General practitioners and paediatricians may encounter APS in patients with one or more vascular thromboses. Because APS is so rare and difficult to diagnosis (risk of overdiagnosis) any suspected case should be confirmed rapidly and sometimes urgently by an APS specialist. First-line treatment of thrombotic events in APS includes heparin followed by long-term anticoagulation with a VKA, usually warfarin. Except in the specific case of stro

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Author

Z. Amoura; B. Bader-Meunier; C. BAL dit Sollier; A. Belot; Y. Benhamou; H. Bezanahary; F. Cohen; N. Costedoat-Chalumeau; L. Darnige; L. Drouet; E. Elefant; A. Harroche; M. Lambert; T. Martin; I. Martin-Toutain; A. Mathian; A. Mekinian; M. Pineton De Chambrun; L. de Pontual; D. Wahl; C. Yelnik; S. Zuily; D. Chauveau; J. Clouscard; C. Frere; E. Hachulla; I. Kone-Paut; D. Lasne; T. Lecompte; V. Le Guern; J. Ni Zard; T. Papo; M. Riviere; N. Schleinitz; B. Tossier

Publisher

Elsevier BV

Published

2023

Language

EN

Field

Medicine (Health Sciences)