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Long-term Effects of Air Pollution on Ankle-brachial Index by Zhang, Siqi; Wolf, Kathrin; Breitner, Susanne; Kronenberg, Florian; Stafoggia, Massimo; Peters, Annette; Schneider, Alexandra is a Environmental Science article available to read on EtoBox.

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## Background: Ankle-brachial index (abi) has been linked to the risk of cardiovascular events. however, the association between long-term exposure to air pollution and abnormal abi has not been fully investigated. ## Methods: This cross-sectional study involved 4544 participants from the kora study (2004-2008) in the region of augsburg, germany. participants' residential annual mean concentrations of particulate matter (pm) and nitrogen dioxide (no) were predicted with land-use regression models, and the traffic information was collected from geographic information systems. we applied multinomial logistic regression models to assess the effects of air pollution on the prevalence of low and high abi, and quantile regression models to explore the non-monotonic relationship between air pollution and abi. we also examined effect modification by individual characteristics. ## Results: Long-term exposure to pm with an aerodynamic diameter ≤ 10 μm (pm) and ≤ 2.5 μm (pm) was significantly associated with a higher prevalence of low abi, with the respective odds ratios (ors) of 1.82 (95%ci: 1.11-2.97) and 1.59 (95%ci: 1.01-2.51) for a 5th to 95th percentile increment in pollutants. positive

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Author

Zhang, Siqi; Wolf, Kathrin; Breitner, Susanne; Kronenberg, Florian; Stafoggia, Massimo; Peters, Annette; Schneider, Alexandra

Publisher

Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0160-4120)

Published

2018

Language

EN

Field

Environmental Science (Physical Sciences)