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Can I read Sex and Gender Perspectives in Colorectal Cancer on EtoBox?
Sex and Gender Perspectives in Colorectal Cancer by I. Baraibar; J. Ros; N. Saoudi; F. Salvà; A. García; M.R. Castells; J. Tabernero; E. Élez is a Medicine article available to read on EtoBox.
What is Sex and Gender Perspectives in Colorectal Cancer about?
Historically women were frequently excluded from clinical trials and drug usage to protect unborn babies from potential harm. As a consequence, the impact of sex and gender on both tumour biology and clinical outcomes has been largely underestimated. Although interrelated and often used interchangeably, sex and gender are not equivalent concepts. Sex is a biological attribute that defines species according to their chromosomal makeup and reproductive organ, while gender refers to a chosen sexual identity. Sex dimorphisms are rarely taken into account, in either preclinical or clinical research, with inadequate analysis of differences in outcomes according to sex or gender still widespread, reflecting a gap in our knowledge for a large proportion of the target population. Underestimation of sex-based differences in study design and analyses has invariably led to ‘one-drug’ treatment regimens for both males and females. For patients with colorectal cancer (CRC), sex also has an impact on the disease incidence, clinicopathological features, therapeutic outcomes, and tolerability to anticancer treatments. Although the global incidence of CRC is higher in male subjects, the proportion o
Who reads Sex and Gender Perspectives in Colorectal Cancer?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- I. Baraibar; J. Ros; N. Saoudi; F. Salvà; A. García; M.R. Castells; J. Tabernero; E. Élez
- Publisher
- Elsevier BV
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)