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Cosmetic adverse effects of antiseizure medications; A systematic review by Ali A. Asadi-Pooya; Marzieh Rostaminejad; Zahra Zeraatpisheh; Nafiseh Mirzaei Damabi is a Medicine article available to read on EtoBox.
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## Background: We systematically reviewed the existing literature on the cosmetic adverse effects of antiseizure medications (asms) in order to depict a clear picture of these unwanted side effects of asms with a particular attention to hair loss, hirsutism, acne, and gingival hyperplasia. ## Methods: This systematic review was prepared according to the recommendations of the preferred reporting items for systematic reviews and meta-analyses (prisma) statement. scopus, medline, and google scholar from the inception to 25 march, 2021 were systematically searched. these key words (title/abstract) were used: "hair loss" or "hirsutism" or "acne" or "gingival hyperplasia" and "seizure" or "epilepsy" or "anriseizure" or "antiepileptic". the exclusion criteria included: non-original studies, articles not in english, and animal studies. ## Results: The primary search yielded 3938 studies; 127 studies were related to the topic and were included in the current systematic review. the most robust evidence on cosmetic adverse effects of asms were related to phenytoin (causing gingival hyperplasia, hirsutism, and acne) and valproate (causing hair loss and hirsutism); however, many other asms wer
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- Author
- Ali A. Asadi-Pooya; Marzieh Rostaminejad; Zahra Zeraatpisheh; Nafiseh Mirzaei Damabi
- Publisher
- Elsevier BV
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)