Can I read GALA Peptide in Acid-Inducible Switch on EtoBox?

GALA Peptide in Acid-Inducible Switch by pj is a document available to read on EtoBox.

What is GALA Peptide in Acid-Inducible Switch about?

This document describes incorporating the GALA peptide into a protein cage to create an acid-inducible molecular switch. The GALA peptide undergoes a coil-to-helix transition when the pH decreases from 7 to 5 due to changes in electrostatic and hydrophobic interactions. The authors genetically modified a ferritin protein cage by inserting GALA peptides of different lengths. They found the engineered cages remained intact at physiological pH but completely dissociated at pH 6, and could be reassembled by neu

Author

pj

Language

EN