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This study investigates the risk of uncomplicated peptic ulcers among users of aspirin and nonaspirin NSAIDs in a cohort of 458,840 individuals in the UK from 1995 to 1999. It found that the relative risk for symptomatic ulcers was significantly higher for both aspirin (2.9) and nonaspirin NSAIDs (4.0), with risks increasing with dosage and duration of use. The findings suggest that NSAIDs may not only complicate but also cause clinically relevant peptic ulcers.

Author

marylanzilli

Language

EN