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What is Angiotensin II and MAPK in Liver Inflammation about?
This review discusses the role of angiotensin II (Ang II) and the mitogen-activated protein kinase (MAPK) pathway in hepatic inflammation. Ang II activates through angiotensin II receptor types 1 and 2 (AT1R and AT2R), and can stimulate free radical production, inflammation, and fibrosis in the liver through MAPK signaling. Activation of MAPK pathways such as p38, ERK1/2, and JNK by Ang II contributes to inflammation by inducing cytokines. The review explores how Ang II and MAPK interactions may promote liv
- Author
- Komang
- Language
- EN