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Long‐term Outcome of Patients with Palindromic Rheumatism Treated with Methotrexate by Arezoo Ghassembaglou; Kamal Esalatmanesh; Leyla Gadakchi; Farnaz Nourmohammadi; Alireza Khabbazi is a Medicine article available to read on EtoBox.
What is Long‐term Outcome of Patients with Palindromic Rheumatism Treated with Methotrexate about?
## Abstract ## Objective Palindromic rheumatism (PR) is characterized by self‐resolving and short duration attacks of arthritis/periarthritis. The present study was performed to report the results of PR treatment with methotrexate (MTX). ## Methods We reviewed the charts of 152 patients with diagnosis of PR. Inclusion criteria were diagnosis of PR according to the criteria of Weismann, age ≥16, active disease and treatment with MTX for at least 6 months. Disease outcome was assessed by reaching remission and prevention of disease evolution to chronic arthritis. Remission was defined as stopping the attacks for 12 weeks and prednisolone dose ≤5 mg/d. MTX treatment failure was defined as failure to achieve remission, the need to add other disease‐modifying antirheumatic drugs and disease progression to chronic arthritis. ## Results Fifty‐nine patients were included in the study. Median duration of follow‐up was 43 months. Attacks were controlled in 89.8% of patients. In 80% of the patients remission occurred during 12 months after starting treatment with MTX. Treatment failed in 20.3% of patients. Wrist joint involvement and positive rheumatoid factor (RF) were significantly more com
Who reads Long‐term Outcome of Patients with Palindromic Rheumatism Treated with Methotrexate?
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- Author
- Arezoo Ghassembaglou; Kamal Esalatmanesh; Leyla Gadakchi; Farnaz Nourmohammadi; Alireza Khabbazi
- Publisher
- Wiley
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)