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What is Metronidazole Colon-Specific Tablets about?

This document summarizes a study that developed and optimized metronidazole compression coated tablets for colon-specific drug delivery. Metronidazole is commonly used to treat intestinal amoebiasis but is rapidly absorbed in the upper gastrointestinal tract, resulting in systemic side effects. The study aimed to formulate a tablet that releases drug in the colon by coating metronidazole cores with varying ratios of chitosan and carbopol 934P. Tablets were evaluated for thickness, weight variation, hardness

Author

Abou Tebba Sam

Language

EN