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Cognition and transcranial sonography in Parkinson's disease patients with or without orthostatic hypotension by Jia‐jing Wu; Hong Jin; Ying‐qi Shao; Cheng‐jie Mao; Jing Chen; Chun‐feng Liu is a Medicine article available to read on EtoBox.

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## Abstract ## Background Orthostatic hypotension (OH) is a common nonmotor symptom in patients with Parkinson's disease (PD), with an incidence ranging from 14% to 54%. ## Aims This study explored changes in cognition and transcranial sonography (TCS) findings in patients with PD and OH. ## Methods We enrolled PD patients who visited the outpatient or inpatient department from 2017 to 2020. Blood pressure was measured in different positions, and demographic data were collected. Motor and nonmotor symptoms were evaluated using standard scales. A subset of 107 patients underwent TCS. ## Results We enrolled 66 PD‐OH patients and 92 PD‐no orthostatic hypotension (NOH) patients. There were no significant differences in gender, age, disease duration, or Hoehn and Yahr stage between groups. Binary logistic regression revealed age as an independent risk factor for OH in PD patients. There were statistically significant group differences in visuospatial and executive function and Unified Parkinson's Disease Rating Scale (UPDRS) I and II scores (p < .05). Among PD‐OH patients, there was a statistically significant difference in UPDRS II and III scores between patients with or without clinic

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Author

Jia‐jing Wu; Hong Jin; Ying‐qi Shao; Cheng‐jie Mao; Jing Chen; Chun‐feng Liu

Publisher

Wiley

Published

2021

Language

EN

Field

Medicine (Health Sciences)