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Studies of He-T DNA sequences in the pericentric regions of Drosophila chromosomes by Karen Lahey Traverse; Mary Lou Pardue is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Studies of He-T DNA sequences in the pericentric regions of Drosophila chromosomes about?

He-T DNA is a complex set of repeated DNA sequences with sharply defined locations in the polytene chromosomes of Drosophila melanogaster. He-T sequences are found only in the chromocenter and in the terminal (telomere) band on each chromosome arm. Both of these regions appear to be heterochromatic and He-T sequences are never detected in the euchromatic arms of the chromosomes (Young et al. 1983). In the study reported here, in situ hybridization to metaphase chromosomes was used to study the association of He-T DNA with heterochromatic regions that are under-replicated in polytene chromosomes. Although the metaphase Y chromosome appears to be uniformly heterochromatic, He-T DNA hybridization is concentrated in the pericentric region of both normal and deleted Y chromosomes. He-T DNA hybridization is also concentrated in the pericentric regions of the autosomes. Much lower levels of He-T sequences were found in pericentric regions of normal X chromosomes; however compound X chromosomes, constructed by exchanges involving Y chromosomes, had large amounts of He-T DNA, presumably residual Y sequences. The apparent co-localization of He-T sequences with satellite DNAs in pericentric h

Who reads Studies of He-T DNA sequences in the pericentric regions of Drosophila chromosomes?

Author

Karen Lahey Traverse; Mary Lou Pardue

Publisher

Springer; Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC (ISSN 0009-5915)

Published

1989

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)