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This review discusses the role of estrogen in modulating osteoclastogenesis through the immune system, particularly focusing on cytokines released by T and B cells. Estrogen influences bone physiology by affecting immune cell activity, which can lead to increased osteoclast activity and bone resorption, especially in postmenopausal women. The interplay between estrogen, immune cells, and bone health highlights the importance of maintaining estrogen levels for preventing conditions like osteoporosis.

Author

Marcelo J B Silva

Language

EN