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AAV9 Capsid Degradation Monitoring Methods by wensregenerate is a document available to read on EtoBox.
What is AAV9 Capsid Degradation Monitoring Methods about?
This study investigates the limitations of anion exchange chromatography (AEX) in monitoring the chemical degradation of AAV9 capsid due to DNA cargo interference, proposing hydrophobic interaction chromatography (HIC) as a reliable alternative. The research demonstrates that AAV9 capsid experiences significant chemical degradation under thermal stress, with HIC providing a more efficient method for characterizing this degradation compared to traditional peptide mapping techniques. The findings highlight th
- Author
- wensregenerate
- Language
- EN