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Effects of Surface Topography and Chemistry on Polyether-Ether-Ketone (PEEK) and Titanium Osseointegration by F. Brennan Torstrick; Angela S.P. Lin; David L. Safranski; Daniel Potter; Todd Sulchek; Christopher S.D. Lee; Ken Gall; Robert E. Guldberg is a Medicine article available to read on EtoBox.

What is Effects of Surface Topography and Chemistry on Polyether-Ether-Ketone (PEEK) and Titanium Osseointegration about?

## Study design: An in vivo study examining the functional osseointegration of smooth, rough, and porous surface topographies presenting polyether-ether-ketone (peek) or titanium surface chemistry. ## Objective: To investigate the effects of surface topography and surface chemistry on implant osseointegration. ## Summary of background data: Interbody fusion devices have been used for decades to facilitate fusion across the disc space, yet debate continues over their optimal surface topography and chemistry. though both factors influence osseointegration, the relative effects of each are not fully understood. ## Methods: Smooth, rough, and porous implants presenting either a peek or titanium surface chemistry were implanted into the proximal tibial metaphyses of 36 skeletally mature male sprague dawley rats. at 8 weeks, animals were euthanized and bone-implant interfaces were subjected to micro-computed tomography analysis (n = 12), histology (n = 4), and biomechanical pullout testing (n = 8) to assess functional osseointegration and implant fixation. ## Results: Micro-computed tomography analysis demonstrated that bone ingrowth was 38.9 ± 2.8% for porous peek and 30.7 ± 3.3% for po

Who reads Effects of Surface Topography and Chemistry on Polyether-Ether-Ketone (PEEK) and Titanium Osseointegration?

Author

F. Brennan Torstrick; Angela S.P. Lin; David L. Safranski; Daniel Potter; Todd Sulchek; Christopher S.D. Lee; Ken Gall; Robert E. Guldberg

Publisher

Ovid Technologies (Wolters Kluwer Health)

Published

2019

Language

EN

Field

Medicine (Health Sciences)