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Leaf-buds of Pistacia atlantica: a novel source of bioactive molecules with high anti-inflammatory, antioxidant, anti-tyrosinase and antimicrobial properties by Assia Benmahieddine; Nabila Belyagoubi-Benhammou; Larbi Belyagoubi; Nesrine Ouda Amari; Asma El Zerey-Belaskri; Angelo Gismondi; Gabriele Di Marco; Antonella Canini; Salim Habi; Fawzia Atik Bekkara; Noureddine Djebli is a Agricultural and Biological Sciences article available to read on EtoBox.
What is Leaf-buds of Pistacia atlantica: a novel source of bioactive molecules with high anti-inflammatory, antioxidant, anti-tyrosinase and antimicrobial properties about?
In this study, for the first time, the anti-inflammatory, antioxidant, anti-tyrosinase and antimicrobial property of P. atlantica Desf. subsp. atlantica leaf-bud extract have been investigated. The anti-inflammatory activity was determined in vivo by reducing carrageenan-induced hind paw edema in mice, while the antiradical function was evaluated using DPPH, total antioxidant capacity (TAC) and reduction power assays. The extract induced a significant reduction of the edema, from 1 to 6 h in a dose-dependent manner (150, 200 and 300 mg/kg). Histological observations of the inflamed tissues also confirmed this. An effective antioxidant activity of the plant samples was demonstrated, showing an EC 50 = 0.183 ± 0.005 mg/mL for the DPPH test, a value of 28.776 ± 2.541 mg AAE/g for the TAC and an EC 50 = 0.136 ± 0.003 mg/mL for reducing power. The leaf-bud extract also revealed a good antimicrobial activity against S. aureus and L. monocytogenes (mean diameter of inhibition zones of 13.2 and 17.0 mm, respectively), while a slight antifungal effect was observed. The plant preparation was then documented to inhibit tyrosinase activity, with an EC 50 value of 0.098 ± 0.00 mg/mL in a dose-d
Who reads Leaf-buds of Pistacia atlantica: a novel source of bioactive molecules with high anti-inflammatory, antioxidant, anti-tyrosinase and antimicrobial properties?
It is typically read by researchers, students, and practitioners in Agricultural and Biological Sciences.
- Author
- Assia Benmahieddine; Nabila Belyagoubi-Benhammou; Larbi Belyagoubi; Nesrine Ouda Amari; Asma El Zerey-Belaskri; Angelo Gismondi; Gabriele Di Marco; Antonella Canini; Salim Habi; Fawzia Atik Bekkara; Noureddine Djebli
- Publisher
- Springer Science and Business Media LLC
- Published
- 2023
- Language
- EN
- Field
- Agricultural and Biological Sciences (Life Sciences)