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Bone bonding ability of an apatite-coated polymer produced using a biomimetic method: A mechanical and histological study in vivo by Masahisa Nagano; Toshiaki Kitsugi; Takashi Nakamura; Tadashi Kokubo; Masami Tanahashi is a Medicine article available to read on EtoBox.
What is Bone bonding ability of an apatite-coated polymer produced using a biomimetic method: A mechanical and histological study in vivo about?
A 20-microns thick apatite layer was coated onto polyethersulfone (PES) rectangular plates by soaking them in simulated body fluid containing CaO-SiO2 based glass powder. Coated and uncoated PES plates (10 x 15 x 1.5 mm) were implanted in the tibiae of rabbits, which were sacrificed 8, 16, and 30 weeks thereafter, and the samples were examined histologically using contact microradiography (CMR), Giemsa surface staining, and a scanning electron microscope connected to an electron probe microanalyzer (SEM-EPMA). The tensile failure loads at the bone/implant interfaces were determined using the detaching test. The histological examinations showed excellent bone apposition on coated PES and the sign of degradation of the apatite layer at remodeling lacunae. The apatite layer underwent complete resorption and was replaced by bone in most areas of the bone/implant interface after 30 weeks. Bone did not bond directly to uncoated PES after each follow-up period. The failure loads between bone and coated PES at 8, 16, and 30 weeks after implantation were 1.7 +/- 0.35, 2.36 +/- 0.53, and 1.45 +/- 0.48 kg, respectively. Those between bone and uncoated PES were nearly 0 kg at each postimplanta
Who reads Bone bonding ability of an apatite-coated polymer produced using a biomimetic method: A mechanical and histological study in vivo?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Masahisa Nagano; Toshiaki Kitsugi; Takashi Nakamura; Tadashi Kokubo; Masami Tanahashi
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); Heterocorporation; Wiley (ISSN 0021-9304)
- Published
- 1996
- Language
- EN
- Field
- Medicine (Health Sciences)