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Association of Metabolic–bariatric Surgery with Long-term Survival in Adults with and Without Diabetes: a One-stage Meta-analysis of Matched Cohort and Prospective Controlled Studies with 174 772 Participants by Nicholas L Syn; David E Cummings; Louis Z Wang; Daryl J Lin; Joseph J Zhao; Marie Loh; Zong Jie Koh; Claire Alexandra Chew; Ying Ern Loo; Bee Choo Tai; Guowei Kim; Jimmy Bok-Yan So; Lee M Kaplan; John B Dixon; Asim Shabbir is a Social Sciences article available to read on EtoBox.
What is Association of Metabolic–bariatric Surgery with Long-term Survival in Adults with and Without Diabetes: a One-stage Meta-analysis of Matched Cohort and Prospective Controlled Studies with 174 772 Participants about?
## Background: Metabolic-bariatric surgery delivers substantial weight loss and can induce remission or improvement of obesity-related risks and complications. however, more robust estimates of its effect on long-term mortality and life expectancy-especially stratified by pre-existing diabetes status-are needed to guide policy and facilitate patient counselling. we compared long-term survival outcomes of severely obese patients who received metabolic-bariatric surgery versus usual care. ## Methods: We did a prespecified one-stage meta-analysis using patient-level survival data reconstructed from prospective controlled trials and high-quality matched cohort studies. we searched pubmed, scopus, and medline (via ovid) for randomised trials, prospective controlled studies, and matched cohort studies comparing all-cause mortality after metabolic-bariatric surgery versus non-surgical management of obesity published between inception and feb 3, 2021. we also searched grey literature by reviewing bibliographies of included studies as well as review articles. shared-frailty (ie, random-effects) and stratified cox models were fitted to compare all-cause mortality of adults with obesity who u
Who reads Association of Metabolic–bariatric Surgery with Long-term Survival in Adults with and Without Diabetes: a One-stage Meta-analysis of Matched Cohort and Prospective Controlled Studies with 174 772 Participants?
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- Author
- Nicholas L Syn; David E Cummings; Louis Z Wang; Daryl J Lin; Joseph J Zhao; Marie Loh; Zong Jie Koh; Claire Alexandra Chew; Ying Ern Loo; Bee Choo Tai; Guowei Kim; Jimmy Bok-Yan So; Lee M Kaplan; John B Dixon; Asim Shabbir
- Publisher
- Elsevier BV
- Published
- 2021
- Language
- EN
- Field
- Social Sciences