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This systematic review and meta-analysis evaluates the efficacy of simultaneous hypertonic saline solution and IV furosemide (HSS+Fx) versus IV furosemide alone (Fx) in patients with fluid overload. The analysis of 11 randomized controlled trials involving 2,987 patients shows that HSS+Fx significantly reduces all-cause mortality, heart failure-related readmissions, and hospital length of stay while improving daily diuresis and renal function. The findings suggest moderate certainty that HSS+Fx is beneficia

Author

rdsreinaldo.silva

Language

EN