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What is Annona Muricata Toxicity in Animal Models about?

This systematic review analyzed the acute, chronic, and sub-chronic toxicity of Annona muricata in mice and rat models. Nine studies met the inclusion criteria examining toxicity through oral and intraperitoneal administration. Results showed mortality up to 2000 mg/kg following acute exposure. Sub-acute testing revealed kidney tissue damage. Toxicity levels varied by solvent, with ethanol and aqueous extracts showing slightly toxic effects at high doses. More research is needed to understand long-term orga

Author

sarahulfaa

Language

EN