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Short-term health-related quality of life, physical function and psychological consequences of severe COVID-19 by Carenzo, Luca (author);Protti, Alessandro (author);Dalla Corte, Francesca (author);Aceto, Romina (author);Iapichino, Giacomo (author);Milani, Angelo (author);Santini, Alessandro (author);Chiurazzi, Chiara (author);Ferrari, Michele (author);Heffler, Enrico (author);Angelini, Claudio (author);Aghemo, Alessio (author);Ciccarelli, Michele (author);Chiti, Arturo (author);Iwashyna, Theodore J. (author);Herridge, Margaret S. (author);Cecconi, Maurizio (author);, the Humanitas COVID-19 Task Force (author) is a Medicine article available to read on EtoBox.

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## Background Survivors of severe COVID-19 are at risk of impaired health-related quality of life (HRQoL) and persistent physical and psychological disability after ICU and hospital discharge. The subsequent social burden is a major concern. We aimed to assess the short-term HRQoL, physical function and prevalence of post-traumatic stress symptoms of invasively mechanically ventilated COVID-19 patients treated in our ICU. ## Methods Prospective, observational cohort study in a follow-up clinic. Patients completed a 6-min walking test (6MWT) to assess their cardio-pulmonary function around 2 months (early follow-up) from hospital discharge, the EQ-5D-5L questionnaire for quality of life assessment around 2 months and at 6 months from hospital discharge and an anonymous web-based Impact of Event Scale-Revised (IES-R) questionnaire for Post-Traumatic Stress symptoms at 2 months. ## Results 47 patients attended our follow-up program, mean age 59 ± 10 years, median pre-morbid Clinical Frailty Scale (CFS) 2 [2–3]. The median distance walked in 6 min was 470 [406–516] m, 83 [67–99]% of the predicted value. Overall 1 out 3 patients and 4/18 (22%) among those with a good functional baseline

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Author

Carenzo, Luca (author);Protti, Alessandro (author);Dalla Corte, Francesca (author);Aceto, Romina (author);Iapichino, Giacomo (author);Milani, Angelo (author);Santini, Alessandro (author);Chiurazzi, Chiara (author);Ferrari, Michele (author);Heffler, Enrico (author);Angelini, Claudio (author);Aghemo, Alessio (author);Ciccarelli, Michele (author);Chiti, Arturo (author);Iwashyna, Theodore J. (author);Herridge, Margaret S. (author);Cecconi, Maurizio (author);, the Humanitas COVID-19 Task Force (author)

Publisher

Springer Science and Business Media LLC

Published

2021

Language

EN

Field

Medicine (Health Sciences)