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Can I read The Role and Specific Mechanism of OCT4 in Cancer Stem Cells: A Review on EtoBox?
The Role and Specific Mechanism of OCT4 in Cancer Stem Cells: A Review by Qi Zhang; Zhenzhen Han; Yanbo Zhu; Jingcheng Chen; Wei Li is a Medicine article available to read on EtoBox.
What is The Role and Specific Mechanism of OCT4 in Cancer Stem Cells: A Review about?
Recently, evidences show that cancer stem cells (CSCs) are a type of cancer cell group with self-renewal and play a huge role in tumor recurrence, metastasis, and drug resistance. Finding new treatment directions and targets for cancer prognosis and reducing mortality has become a top priority. OCT4, as a transcription factor, participates in maintaining the stem characteristics of CSCs, but the mechanism of OCT4 is often overlooked. In this review, we try to illustrate the mechanism by which OCT4 plays a role in CSCs from the perspective of genetic modification of OCT4, non-coding RNA, complexes and signaling pathways associated with OCT4. Our ultimate goal is to provide new targets for cancer treatment to prolong the survival of cancer patients.
Who reads The Role and Specific Mechanism of OCT4 in Cancer Stem Cells: A Review?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Qi Zhang; Zhenzhen Han; Yanbo Zhu; Jingcheng Chen; Wei Li
- Publisher
- Korean Society for Stem Cell Research
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)
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