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Controlling Nutritional Status (CONUT) score is a prognostic factor in patients with resected breast cancer by Li, Wen; Li, Min; Wang, Ting; Ma, Guangzhi; Deng, Yunfu; Pu, Dan; Liu, Zhenkun; Wu, Qiang; Liu, Xuejuan; Zhou, Qinghua is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Controlling Nutritional Status (CONUT) score is a prognostic factor in patients with resected breast cancer about?
The present study aimed to determine the correlation between controlling nutritional status (CONUT) and prognosis in resected breast cancer patients. Totally, 861 breast cancer patients with surgical resection in West China Hospital of Sichuan University between 2007 and 2010 were included. The relationship between CONUT and various clinicopathological factors as well as prognosis was evaluated. The results showed that the optimal cutoff value for CONUT to predict the 5-year survival was 3 and CONUT had a higher area under the ROC curve (AUC) for 5-year disease free survival (DFS) and overall survival (OS) prediction compared with the neutrophil lymphocyte ratio (NLR) and prognostic nutritional index (PNI). High CONUT was significantly correlated with older age, lymph node involvement, advanced T-stage, and surgery type. In the multivariate analysis, CONUT-high patients had worse DFS and OS, when compared with CONUT-low patients. In conclusion, preoperative CONUT is a useful marker for predicting long term outcomes in breast cancer patients after curative resection.
Who reads Controlling Nutritional Status (CONUT) score is a prognostic factor in patients with resected breast cancer?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Li, Wen; Li, Min; Wang, Ting; Ma, Guangzhi; Deng, Yunfu; Pu, Dan; Liu, Zhenkun; Wu, Qiang; Liu, Xuejuan; Zhou, Qinghua
- Publisher
- Springer Science and Business Media LLC; London: Nature Publishing Group; [London]: Springer Nature; Nature Publishing Group; Society for Mining, Metallurgy and Exploration Inc.; Research Square; Springer Nature; Island Press (ISSN 2045-2322)
- Published
- 2020
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)