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Can I read Granulomatous Slack Skin Disease – Disease Features and Response to Pentostatin on EtoBox?
Granulomatous Slack Skin Disease – Disease Features and Response to Pentostatin by Nnenna Osuji; Louise Fearfield; Estella Matutes; Andrew C. Wotherspoon; Christopher Bunker; Daniel Catovsky is a Medicine article available to read on EtoBox.
What is Granulomatous Slack Skin Disease – Disease Features and Response to Pentostatin about?
**Summary.** Granulomatous slack skin disease (GSSD) is a rare condition characterized clinically by redundant skin folds, which show a predilection towards flexural areas, and histologically by a granulomatous T‐cell infiltrate and loss of elastic fibres. The disease is often indolent, although rapid progression and transformation have been described. There is much debate as to whether this condition is a subset of mycosis fungoides or a separate disease entity in itself. We describe a case of GSSD with unique manifestations including granulomatous bone marrow involvement and hypercalcaemia. The patient has twice achieved a good response to pentostatin after failure of combination chemotherapy. This is the first report of the successful use of the purine analogue pentostatin in the management of GSSD.
Who reads Granulomatous Slack Skin Disease – Disease Features and Response to Pentostatin?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Nnenna Osuji; Louise Fearfield; Estella Matutes; Andrew C. Wotherspoon; Christopher Bunker; Daniel Catovsky
- Publisher
- John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0007-1048)
- Published
- 2003
- Language
- EN
- Field
- Medicine (Health Sciences)