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A phase 3b trial evaluated the efficacy and safety of gefapixant in reducing cough-induced stress urinary incontinence (CSUI) in women with chronic cough. The study found that gefapixant significantly reduced CSUI episodes compared to placebo, with a treatment difference of -11.7% (p=0.004) and a majority of participants experiencing at least one adverse event. This indicates gefapixant is the first treatment to demonstrate efficacy in this specific patient population, addressing a significant unmet medical

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usmleusmle86

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EN