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HNE-Induced G1 Arrest in Yeast Cells by neven.zarkovic is a document available to read on EtoBox.
What is HNE-Induced G1 Arrest in Yeast Cells about?
The study investigates the effects of 4-hydroxy-2-nonenal (HNE) on the cell cycle of the yeast Saccharomyces cerevisiae, revealing that HNE treatment induces a temporary cell cycle arrest in the G1 phase. This arrest is characterized by an increase in G0/G1 cells and a decrease in S-phase cells, with DNA synthesis being particularly affected. The findings suggest that HNE causes a biphasic modulation of cell proliferation, highlighting the utility of yeast as a model for studying the impacts of lipid peroxi
- Author
- neven.zarkovic
- Language
- EN