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What is RP-HPLC Method for Nitroxynil Analysis about?

The study presents the development and validation of a stability-indicating RP-HPLC method for the quantitative determination of Nitroxynil (NTX) and its impurities, adhering to ICH guidelines. The method successfully separates NTX, its impurity 4-Hydroxy-3-nitrobenzonitrile, and the starting material 4-cyanophenol, demonstrating robust performance with a calibration curve ranging from 0.5 to 7.5 ppm. The method is validated for specificity, precision, and accuracy, confirming its applicability for quality

Author

Santosh Kumar Tata

Language

EN