About this document
Advancements in Stapled Peptide Therapeutics by havadese.tarikhi is a document available to read on EtoBox.
The document discusses the development and evaluation of stapled peptides, particularly ALRN-6924 and SAH-SOS1a, for targeting Ras and other small GTPases in cancer treatment. While ALRN-6924 showed improved potency and chemoprotective effects, its clinical efficacy was not statistically significant, leading to the cessation of its development. The research highlights the potential of stapled peptides as therapeutics for challenging protein-protein interactions, demonstrating promising results in preclinica
- Author
- havadese.tarikhi
- Language
- EN