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Can I read New PET Radiotracers for the Imaging of Neuroendocrine Neoplasms on EtoBox?
New PET Radiotracers for the Imaging of Neuroendocrine Neoplasms by Emilia Fortunati; Giulia Argalia; Lucia Zanoni; Stefano Fanti; Valentina Ambrosini is a Medicine article available to read on EtoBox.
What is New PET Radiotracers for the Imaging of Neuroendocrine Neoplasms about?
## Opinion statement Neuroendocrine neoplasms (NEN) are a heterogeneous group of tumours derived from cells of neuroendocrine origin and can potentially arise everywhere in the human body. The diagnostic assessment of NEN can be performed using a variety of PET radiopharmaceuticals. Well-differentiated NEN (NET) present a high expression of SSTR (somatostatin receptors) and can therefore be studied with 68Ga-DOTA-peptides ([68Ga]Ga-DOTANOC, [68Ga]Ga-DOTATOC, [68Ga]Ga-DOTATATE). Current guidelines recommend the use of SSTR imaging to assess disease extension at staging/restaging, follow-up, assessment of response to therapy and selection of patients who may benefit from radionuclide therapy (PRRT). [18F]F-FDG is used for the assessment of high-grade tumours (high-grade G2, G3 and NEC) and in every case, there is one or more mismatched lesions between diagnostic CT (positive) and SSTR-PET/CT (negative). [18F]F-DOPA is currently used for the assessment of medullary thyroid carcinoma, neuroblastoma, primary pheochromocytoma and abdominal paraganglioma. In recent years, however, several new tracers were designed exploiting the many potential targets of the neuroendocrine cell and were e
Who reads New PET Radiotracers for the Imaging of Neuroendocrine Neoplasms?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Emilia Fortunati; Giulia Argalia; Lucia Zanoni; Stefano Fanti; Valentina Ambrosini
- Publisher
- Springer Science and Business Media LLC
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)