Can I read A Novel Continuous Subcutaneous Lactate Monitoring System☆ on EtoBox?
A Novel Continuous Subcutaneous Lactate Monitoring System☆ by A. Poscia; D. Messeri; D. Moscone; F. Ricci; F. Valgimigli is a Engineering article available to read on EtoBox.
What is A Novel Continuous Subcutaneous Lactate Monitoring System☆ about?
A novel continuous lactate monitoring system has been developed modifying the GlucoDay ® portable medical device (A. Menarini Diagnostics), already present in the European market, and used to continuously measure glucose levels. Lactate oxidase based biosensors have been developed immobilising the enzyme on nylon net and placing it on a Pt electrode. The biosensor was connected to the portable device provided with a micro-pump and coupled to a microdialysis system. It is capable to record subcutaneous lactate every 3 min. In vitro analytical results confirmed that the sensors respond linearly in the interval of concentration between 0.1 and 10 mmol/L, covering the whole physiological range. During prolonged monitoring periods, the response of the biosensors remained stable, showing a limited drift of 8%, within 60 h. Stability tests are still on route. However, preliminary results have shown a shelf life of about 10 months. In vivo experiments performed on healthy rabbits have demonstrated the good accuracy and reproducibility of the system. A correlation coefficient equal to 0.9547 (N = 80) was found, which represents a good correlation between the GlucoDay ® and the laboratory re
Who reads A Novel Continuous Subcutaneous Lactate Monitoring System☆?
It is typically read by researchers, students, and practitioners in Engineering.
- Author
- A. Poscia; D. Messeri; D. Moscone; F. Ricci; F. Valgimigli
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0956-5663)
- Published
- 2005
- Language
- EN
- Field
- Engineering (Physical Sciences)